He took up Muay Thai at the age of 14, as a way to defend himself after being attacked on the street. His mother is of Belizean and Irish descent, his father is of Haitian and Dominican descent. Miller was born and raised in Brooklyn, New York. In 2018, Miller was ranked as the world's seventh-best heavyweight by BoxRec, and eighth by The Ring.
Miller was due to challenge Anthony Joshua for the WBA (Super), IBF, WBO, and IBO heavyweight titles in 2019, but was denied a license to box after failing multiple drug tests. He first came to prominence in 2007 when he competed for the New Jersey Tigers in the World Combat League and made it to the finals of the New York Golden Gloves tournament that same year. Jarrell Miller (born July 15, 1988) is an American professional boxer and former kickboxer who competes in the heavyweight division.